TRK fused gene Mouse anti-Human, Clone: OTI2C3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525759
DescriptionTFG protein, a recently identified novel protein, is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region followed by octicosapeptide repeats. Research shows that TFG can modulate SHP-1 activity and is a novel member of the NF-kB pathway. The physiological functions of this protein remain largely elusive, but TFG is thought to function by associating with other proteins, including TANK and NEMO. TFG was first identified as a partner of NTRK1 and is involved in generating the thyroid TRK-T3 oncogene, as well as oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.
|TRK fused gene|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|TF6; HMSNP; SPG57; TRKT3;|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of TFG produced in HEK293T cell|
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