TFPI Monoclonal Antibody (OTI1E1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA805675

Catalog No. 50-168-0807

Description

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predomitly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.

Specifications

• Antigen: TFPI
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P10646
• Gene Symbols: TFPI
• Immunogen: Human recombit protein fragment corresponding to amino acids 29-304 of human TFPI produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1E1
• Conjugate: Unconjugated
• Gene: TFPI
• Gene Alias: EPI, LACI, TFI, TFPI1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7035
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid