TFPI Mouse anti-Human, Clone: OTI4H9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526775
DescriptionTissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predomitly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); TFPI; EPI; LACI; TFI; TFPI1; OTTHUMP00000163472; OTTHUMP00000205431; anti-convertin; extrinsic pathway inhibitor; lipoprotein-associated coagulation inhibitor; tissue factor pathway inhibitor|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 29-304 of TFPI produced in E.coli|
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