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TFPI Mouse anti-Human, Clone: OTI5A2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526774

Catalog No. PIMA526774


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Description

Description

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predomitly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.
Specifications

Specifications

TFPI
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P10646
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); TFPI; EPI; LACI; TFI; TFPI1; OTTHUMP00000163472; OTTHUMP00000205431; anti-convertin; extrinsic pathway inhibitor; lipoprotein-associated coagulation inhibitor; tissue factor pathway inhibitor
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7035
Immunohistochemistry (Paraffin), Western Blot
OTI5A2
Unconjugated
TFPI
Liquid
TFPI
Human recombit protein fragment corresponding to amino acids 29-304 of TFPI produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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