TfR (Transferrin R) Antibody (66IG10), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2329460.02MG

Catalog No. NBP232946F

Description

TfR (Transferrin R) Monoclonal specifically detects TfR (Transferrin R) in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: TfR (Transferrin R)
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: CD71 antigen, CD71TRFR, p90, T9, TfR, TFR1, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr
• Host Species: Mouse
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: It recognizes a ∼90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), SDS-Page
• Clone: 66IG10
• Dilution: Western Blot 0.25-0.5ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page
• Gene Accession No.: P02786
• Gene Symbols: TFRC
• Immunogen: Human thymocytes (T-cells)
• Quantity: 0.02 mg
• Research Discipline: Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Signal Transduction, Stem Cell Markers
• Gene ID (Entrez): 7037
• Target Species: Human
• Form: Purified