TGF-alpha Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 223081AP
DescriptionTransforming growth factor (TGF) alpha is a 50-aa single-chain polypeptide derived from cleavage of transmembrane pro-TGF alpha. Sharing 42% identity with epidermal growth factor (EGF), TGF alpha binds the EGF receptor and activates downstream signaling pathways. TGF alpha is expressed by activated macrophages, keratinocytes, epithelial cells, and a variety of tumor-derived and transformed cell lines. This growth factor mediates cell proliferation and migration, as well as cellular transformation. Overexpression of TGF alpha has been linked to a variety of cancers, including the breast, colon, and stomach.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|EGF like TGF, ETGF, TFGA, TGF alpha, TGF type 1, TGFA|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|Antigen Affinity Chromatography|
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