TGFBR2 Mouse anti-Human, Clone: OTI4F3, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA808048

Catalog No. 50-168-1894

Description

The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Specifications

• Antigen: TGFBR2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P37173
• Gene Symbols: TGFBR2
• Immunogen: Human recombit protein fragment corresponding to amino acids 23-294 of human TGFBR2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI4F3
• Conjugate: Unconjugated
• Gene: TGFBR2
• Gene Alias: AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7048
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid