Invitrogen™ THAP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567164

Catalog No. PIPA567164

Description

Immunogen sequence: VNLSVFCDHNY TVEDTMHQRK RIHQLEQQVE KLRKKLKTAQ QRCRRQERQL EKLKEVVHFQ KEKDDVSERG YVILPNDYF Highest antigen sequence identity to the following orthologs - mouse 95%, rat 94%.

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.

Specifications

• Antigen: THAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Thap1
• Gene Alias: 4833431A01Rik; AW490810; DYT6; nuclear proapoptotic factor; THAP domain containing 1; THAP domain containing, apoptosis associated protein 1; THAP domain protein 1; THAP domain-containing apoptosis-associated protein 1; THAP domain-containing protein 1; THAP1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55145
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NVV9
• Gene Symbols: Thap1
• Immunogen: Recombinant Human THAP1. Recombinant protein control fragment (Product #RP-107813).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG