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Themis Rat anti-Mouse, PE, Clone: 1TMYS, eBioscience™ Invitrogen™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Catalog No. 12-591-880


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Description

Description

This 1TMYS MAb reacts with mouse Thymocyte-expressed molecule involved in selection (Themis), also known as Grb2-associating protein (Gasp). Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes. Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells. In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling. There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing. The 1TMYS antibody recognizes isoforms 1, 2, 3, and 4, but does not recognize isoform 5.

Themis Monoclonal antibody specifically detects Themis in Mouse samples. It is validated for Flow Cytometry
Specifications

Specifications

Themis
Flow Cytometry
1TMYS
PE
Themis
bA325O24.3; bA325O24.4; C6orf190; C6orf207; E430004N04Rik; FLJ40584; GASP; GRB2-associated protein; Grb2-associating protein; MGC163388; Protein THEMIS; Protein thylex; RGD1560849; signaling phosphoprotein specific for T cells; SPOT; Themis; thylex; thymocyte expressed molecule involved in selection; thymocyte selection associated; thymocyte selection pathway associated; thymocyte-expressed molecule involved in selection; TSEPA
IgG2a, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
210757
Liquid
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q8BGW0
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
SDS
Documents
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