Thermo Scientific Lab Vision Insulin Receptor (α -Subunit) Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in experiments with the Thermo Scientific Insulin Receptor (α-Subunit) Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific MS631P
Ensure accurate, reproducible results in experiments with the Thermo Scientific Insulin Receptor (α-Subunit) Ab-1, Mouse Monoclonal Antibody.The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain, whereas the α-subunit (135kDa) is completely extracellular.
Host Species: Mouse
Species Reactivity: Human. Weakly with Cow, Pig and Sheep. Does not react with rabbit, mouse and rat. Others not known.
Epitope: aa 469-592 (exon 7/8)
Immunogen: IM-9 lymphocytes followed by purified insulin receptor
Molecular Weight: 135kDa
Positive Control: IM-9 lymphocyte cells, Placenta
Cellular Localization: Membrane Ab-1 inhibits insulin binding and mimics insulin action. It is excellent for immunoprecipitation of alpha-subunit of IR.
- Insulin-like Agonist
- Inhibits (~80%) Insulin Binding (10nM)
- Tyrosine Kinase Assay (Ab-mediated capture on microplates)
USA: RUO; Int'l: RUO
|Insulin Receptor (alpha-Subunit) Ab-1|
|IM-9 lymphocytes followed by purified insulin receptor|
|Steroids Hormones and Growth Factors|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.