Invitrogen™ Human MMP-24 Recombinant Protein

Recombinant Protein

Supplier:  Invitrogen™ RP77536

Catalog No. PIRP77536

Description

MMP24 Recombinant Protein, RP-77536, from Invitrogen.

RP-77536 is a purified recombinant MMP-24 (catalytic domain) protein purified from E. coli periplasm. MT5-MMP catalytic domain is produced by activation of a recombinant soluble proform of MT5-MMP. Activation generates two molecular species. One species begins at the N-terminus with Tyr156 of full-length MT5-MMP, while the other species is two amino acid residues shorter and starts with Leu158. Both species extend to Ser351 of MT5-MMP and they contain an additonal His-tag sequence at the C-terminal. The specific activity of MT5-MMP catalytic domain is greater than 120 mU/mg. 1 U is the activity that hydrolyzes 1μmol peptide (7-methoxycoumarin-4-yl) acetyl-Pro-Leu-Gly-Leu-(3-[2,4-dinitrophenyl]-L-2,3- diamino-propionyl)-Ala-Arg-NH2 (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg) within 1 min. The catalytic domain of MT5-MMP is inhibited by tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) and by chelators of divalent cations like EDTA or o-phenanthroline.

Specifications

• Accession Number: Q9Y5R2
• Formulation: TBS with 5mM CaCl2 and no preservative; pH 7.5
• Name: Human MMP24
• Quantity: 10μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Gene Alias: MT5-MMP
• Gene Symbol: MMP24
• Conjugate: Unconjugated
• Species: E. coli
• Form: Liquid
• Purity or Quality Grade: purified

• For Use With (Application): Control
• Gene ID (Entrez): 10893
• pH Range: 7.5
• Source: E. coli
• Regulatory Status: RUO
• Common Name: Human MMP24
• Specific Reactivity: Human
• Cross Reactivity: Hu
• Recombinant: Recombinant
• Protein Subtype: Recombinant

Safety and Handling

ShelfLife : 12 Months

in vitro research only