Thrombospondin (TSP) Ab-1 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ Thrombospondin (TSP) Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia MS418P1ABX

Catalog No. MS418P1ABX

Description

Thrombospondin is a protein from platelet a-granules. It is made up of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.

Host Species: Mouse

Clone: A4.1

Isotype: IgM

Species Reactivity: Human, Mouse, Rat, Cow and Chicken. Others not known.

Epitope: N-terminal half of the central stalk-like region of TSP, which is recovered as a 50kDa fragment after chymotryptic digestion of TSP

Immunogen: Calcium-replete, native purified human TSP from the supernatant of thrombin-activated platelets

Molecular Weight: ∽450kDa (nonreduced)

Positive Control: HUVEC cells

Cellular Localization: Secretory granules, Golgi complex, endoplasmic reticulum, extracellular matrix

Recommended for:

• Immunohistochemistry (Not suitable)
• Western Blotting (Nonreduced only)
• Immunofluorescence
• Blocks Binding of TSP-1 to TSP-Rec./CD36
• Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Thrombospondin (TSP) Ab-1
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Angiogenesis
• Target Species: Bovine, Chicken, Human, Mouse, Rat
• Isotype: IgM

• Applications: Flow Cytometry, Immunofluorescence, Western Blot
• Clone: A4.1
• Conjugate: Unconjugated
• Immunogen: Calcium-replete, native purified human TSP from the supernatant of thrombin-activated platelets
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated