Invitrogen™ Thromboxane Synthase Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102542

Catalog No. PIPA5102542

Description

Antibody detects endogenous levels of total TBXAS1.

Thromboxane synthase encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Thromboxane Synthase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TBXAS1
• Gene Alias: BDPLT14; CYP5; Cyp5a1; cytochrome P450 5A1; cytochrome P450, family 5, subfamily A, polypeptide 1; FLJ52771; GHOSAL; platelet, cytochrome P450, subfamily V; similar to Thromboxane-A synthase (TXA synthase) (TXS); Tbxas1; THAS; ThromboxA ane synthase 1; thromboxane A synthase 1; thromboxane A synthase 1 (platelet); thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A); thromboxane A synthase 1, platelet; thromboxane synthase; thromboxane-A synthase; TS; TXA synthase; TXAS; TXS
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21391, 24886, 6916
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P24557, P36423, P49430
• Gene Symbols: TBXAS1
• Immunogen: A synthesized peptide derived from human TBXAS1(Accession P24557), corresponding to amino acid residues P49-V99.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG