Thymidine Phosphorylase/PD-ECGF Ab-1 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ Thymidine Phosphorylase/PD-ECGF Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia MS499P1

Catalog No. MS499P1

Description

Platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

Host Species: Mouse

Clone: P-GF.44C

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant full-length human thymidine phosphorylase (TP/PD-ECGF) protein

Molecular Weight: 55kDa (reduced)

Positive Control: HUVEC cells, Breast CA

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting (Not verified)
• Neutralizes Enzymatic Activity of TP/PD-ECGF (Not verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Thymidine Phosphorylase/PD-ECGF Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 500 μL
• Research Discipline: Angiogenesis
• Target Species: Human, Mouse, Rat
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: P-GF.44C
• Conjugate: Unconjugated
• Immunogen: Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated