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Thyroid Peroxidase Mouse anti-Human, Clone: TPO28, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524786

Catalog No. PIMA524786


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Description

Description

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined.
Specifications

Specifications

Thyroid Peroxidase
Monoclonal
Unconjugated
TPO
Liquid
TPO
Full length human thyroid peroxidase and spleen cells of Balb/c mice.
Protein A
RUO
Antibody
Monoclonal
Human
ELISA, Western Blot
TPO28
PBS with 0.09% sodium azide; pH 7.4
P07202
EC 1.11.1, MSA, TDH2A, thyroid microsomal antigen, thyroid peroxidase, thyroperoxidase, TPXEC 1.11.1.8
Mouse
IgG1
250 μg
4° C, do not freeze
Primary
7173
Documents
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