Thyroid Peroxidase Mouse anti-Human, Clone: TPO28, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524786
DescriptionThis gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined.
|Full length human thyroid peroxidase and spleen cells of Balb/c mice.|
|ELISA, Western Blot|
|PBS with 0.09% sodium azide; pH 7.4|
|EC 1.11.1, MSA, TDH2A, thyroid microsomal antigen, thyroid peroxidase, thyroperoxidase, TPXEC 220.127.116.11|
|4° C, do not freeze|
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