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TIAM2 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548604

Catalog No. PA548604


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Description

Description

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane. Activates specifically RAC1, but not CDC42 and RHOA.
Specifications

Specifications

TIAM2
Polyclonal
PBS with 0.09% sodium azide
Q6ZPF3
T-lymphoma invasion and metastasis-inducing protein 2, TIAM-2, SIF and TIAM1-like exchange factor, TIAM2, KIAA2016, STEF
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
24001
Western Blot
Unconjugated
Tiam2
Liquid
TIAM2
KLH conjugated synthetic peptide between 357-385 amino acids from the N-terminal region of human TIAM2.
Protein A, Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse
Documents
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