TIAM2 Rabbit anti-Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA548604
DescriptionModulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane. Activates specifically RAC1, but not CDC42 and RHOA.
|PBS with 0.09% sodium azide|
|T-lymphoma invasion and metastasis-inducing protein 2, TIAM-2, SIF and TIAM1-like exchange factor, TIAM2, KIAA2016, STEF|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 357-385 amino acids from the N-terminal region of human TIAM2.|
|Protein A, Antigen Affinity Chromatography|
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