TICAM1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 232881AP
DescriptionInvolved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|PRVTIRB, TICAM 1, TICAM1, TRIF|
|Immunohistochemistry (Paraffin), Western Blot|
|TRIF/TICAM1 Fusion Protein Ag19779|
|Antigen Affinity Chromatography|
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