TRIF Mouse anti-Human, Non-human primate, Clone: OTI1G7, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526477
DescriptionTRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3. TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappa-B.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|PRVTIRB, TICAM-1, TRIF, TIR domain containing adaptor inducing interferon-beta, TIR domain-containing adapter molecule 1, TIR domain-containing adapter protein inducing IFN-beta, proline-rich, vinculin and TIR domain-containing protein B, putative NF-kappa-B-activating protein 502H, toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta|
|-20° C, Avoid Freeze/Thaw Cycles|
|Human recombit protein fragment corresponding to amino acids 120-420 of TICAM1 produced in E.coli|
|Human, Non-human primate|
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