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TICAM2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548656

Catalog No. PA548656

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

TRAM, or TRIF-related adaptor molecule (TICAM2), plays an essential role in the MyD88-independent signaling of TLR4. The functional absence of TRAM in vascular endothelial cells restricts TLR4 signaling to MyD88-dependent pathway. Overexpression of TRAM cDNA in endothelial cells reconstituted LPS-induced Trif-dependent NF-kB activation and cxcl10 promoter activity.
Specifications

Specifications

TICAM2
Polyclonal
PBS with 0.09% sodium azide
Q86XR7
TIR domain-containing adapter molecule 2, TICAM-2, Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein, MyD88-4, TICAM2, TIRAP3, TIRP, TRAM
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
353376
Western Blot
Unconjugated
TICAM2
Liquid
TICAM2
KLH conjugated synthetic peptide between 12-41 amino acids from the N-terminal region of human TICAM2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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