TICAM2 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 195241AP150UL
DescriptionTRAM, or TRIF-related adaptor molecule (TICAM2), plays an essential role in the MyD88-independent signaling of TLR4. The functional absence of TRAM in vascular endothelial cells restricts TLR4 signaling to MyD88-dependent pathway. Overexpression of TRAM cDNA in endothelial cells reconstituted LPS-induced Trif-dependent NF-kB activation and cxcl10 promoter activity.
|TICAM 2, TICAM2, TIRAP3, TIRP, TRAM, TRIF related adapter molecule|
|Antigen Affinity Chromatography|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
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