TIM-4, Rabbit anti-Mouse, Clone: 5G3, Novus Biologicals™

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP2811210.2MG

Catalog No. NB016578

Description

TIM-4 Monoclonal specifically detects TIM-4 in Mouse samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Block/Neutralize.

Specifications

• Antigen: TIM-4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Block/Neutralize
• Gene Alias: FLJ27515, SMUCKLER, T-cell immunoglobulin and mucin domain containing 4, T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM4, TIM-4, TIMD-4
• Host Species: Rabbit
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Gene ID (Entrez): 91937
• Target Species: Mouse
• Form: Purified

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence, Blocking Assay
• Clone: 5G3
• Conjugate: Unconjugated
• Formulation: PBS
• Gene Symbols: TIMD4
• Immunogen: This antibody was raised by immunising female Lewis rats (Harlan Sprague-Dawley) with Tim-4:Ig fusion protein in complete Freund's adjuvant.
• Quantity: 0.2 mg
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific for murine TIM-4, which unlike other TIM family members, is not expressed on T lymphocytes but rather found on antigen presenting cells such as lymphoid and myeloid DC's and macrophages. TIM-4 has been shown to interact with TIM-1 thereby suggesting a role of TIM-4 in the balance of Th1/Th2 regulation. Additionally TIM-4 has been shown to be a receptor for phosphatidylserine and may play a role in engulfment of apoptotic cells.
• Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Isotype: IgG κ