TIMP2 Mouse anti-Human, Clone: 3A4, Abnova™
Mouse monoclonal antibody raised against human TIMP2.
Manufacturer: Abnova Corporation MAB12979
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq]
|Mouse monoclonal antibody raised against human TIMP2.|
|In PBS (0.08% sodium azide).|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|ELISA, Immunohistochemistry (PFA fixed), Western Blot|
|ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL) Western Blot The optimal working dilution should be determined by the end user.|
|Protein A/G purification|
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