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Tocris Bioscience™ Tiplaxtinin
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
$200.68 - $841.00
Specifications
| Chemical Name or Material | α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid |
|---|---|
| CAS | 393105-53-8 |
| Synonym | PAI 039, tiplasinin |
| Target | Additional Synthetic Protease Inhibitors |
| Molecular Formula | C24H16F3NO4 |
Description
Plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC50 = 2.7 μM). Induces vascular smooth muscle cell apoptosis in vitro and reduces carotid artery neointimal formation in a rat vascular injury model. Promotes thrombolysis in rat and dog models of acute arterial thrombosis. Orally available.Specifications
| α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid | |
| PAI 039, tiplasinin | |
| C24H16F3NO4 | |
| >98% |
| 393105-53-8 | |
| Additional Synthetic Protease Inhibitors | |
| 439.38 |
Safety and Handling
Recommended Storage : Store at 4°C
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