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Tocris Bioscience™ TL 0259

Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable

$261.50 - $1102.00

Specifications

Chemical Name or Material 3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride
Molecular Formula C32H34F3N5O4.2HCl
Purity 98%
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
69-811-0
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Tocris Bioscience™
6981/10
10 mg
Each for $261.50
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69-815-0
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Tocris Bioscience™
6981/50
50 mg
Each for $1,102.00
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Description

Description

  • Selective and highly potent Fgr and Lyn inhibitor (IC50 values are 0.03 and 0.1 nM, respectively).
  • Exhibits selectivity for Fgr and Lyn over other Src family kinases and other nonreceptor and receptor tyrosine kinases.
  • Suppresses proliferation of acute myelogenous leukemia (AML) cell lines in vitro.
  • Eliminates leukemic cells from spleen and bone of mice bearing AML xenografts.
  • Orally bioavailable.
Specifications

Specifications

3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride
C32H34F3N5O4.2HCl
98%
SDS
Product Certifications
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