TLR12 Monoclonal Antibody (15F1215), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA141484

Catalog No. 01-676-619

Description

Based on sequence homology, this antibody may also detect mouse TLR11.

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands.

Specifications

• Antigen: TLR12
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites diluted in PBS with 0.2% gelatin and 0.05% sodium azide
• Gene Accession No.: Q6QNU9
• Gene Symbols: Tlr12
• Immunogen: Amino acids 791-821 of mouse TLR12
• Regulatory Status: RUO
• Gene ID (Entrez): 384059
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Clone: 15F1215
• Conjugate: Unconjugated
• Gene: Tlr12
• Gene Alias: Gm1365; Gm287; MGC129352; MGC129353; RGD1559145; Tlr11; Tlr12; Toll-like receptor 11; Toll-like receptor 12
• Host Species: Mouse
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgM

Safety and Handling

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