TLR2 Mouse, Clone: TLR2/221, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2477470.1MG

Catalog No. NBP247747A

Description

TLR2 Monoclonal specifically detects TLR2 in Human, Canine, Monkey samples. It is validated for Functional.

Specifications

• Antigen: TLR2
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
• Gene Alias: CD282 antigen, TIL4CD282, toll/interleukin 1 receptor-like 4, Toll/interleukin-1 receptor-like protein 4, toll-like receptor 2
• Host Species: Mouse
• Molecular Weight of Antigen: 90 kDa
• Quantity: 0.1 mg
• Research Discipline: Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Toll Like Receptors
• Gene ID (Entrez): 7097
• Target Species: Human, Canine, Monkey
• Form: Purified

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
• Clone: TLR2/221
• Conjugate: Unconjugated
• Formulation: PBS with No Preservative
• Gene Symbols: TLR2
• Immunogen: Recombinant human TLR2 protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG2a κ