TLR3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 177661AP
DescriptionTLR3 is involved in Herpes simplex encephalitis 2 (HSE2), a rare complication of human herpesvirus 1 (HHV-1) infection, occurring in only a small minority of HHV-1 infected individuals. HSE is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is over several days and involves fever, headache, seizures, stupor, and often coma, frequently with a fatal outcome. Disease susceptibility is associated with variations affecting the gene represented in this entry. TLR3 mutations predispose otherwise healthy individuals to isolated herpes simplex encephalitis through a mechanism that involves impaired IFNs production and reduced immune defense against viral infection in the central nervous system.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|CD283, TLR3, toll like receptor 3|
|142980, 364594, 7098|
|Flow Cytometry, Immunohistochemistry (Paraffin)|
|TLR3 Fusion Protein Ag12171|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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