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TLR3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 177661AP

Catalog No. 50-173-1777


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Description

Description

TLR3 is involved in Herpes simplex encephalitis 2 (HSE2), a rare complication of human herpesvirus 1 (HHV-1) infection, occurring in only a small minority of HHV-1 infected individuals. HSE is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is over several days and involves fever, headache, seizures, stupor, and often coma, frequently with a fatal outcome. Disease susceptibility is associated with variations affecting the gene represented in this entry. TLR3 mutations predispose otherwise healthy individuals to isolated herpes simplex encephalitis through a mechanism that involves impaired IFNs production and reduced immune defense against viral infection in the central nervous system.
Specifications

Specifications

TLR3
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O15455, Q99MB1
CD283, TLR3, toll like receptor 3
Rabbit
IgG
150 μL
-20°C
Primary
142980, 364594, 7098
Flow Cytometry, Immunohistochemistry (Paraffin)
Unconjugated
TLR3
Liquid
Tlr3
TLR3 Fusion Protein Ag12171
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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