Invitrogen™ TLR9 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA517493

Catalog No. PIPA517493

Description

It is not recommended to aliquot this antibody.

The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Specifications

• Antigen: TLR9
• Classification: Polyclonal
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: Q9NR96
• Gene Symbols: Tlr9
• Immunogen: Synthetic peptide corresponding to residues surrounding Gly442 of human TLR9 protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene: Tlr9
• Gene Alias: CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54106
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov