Tocris™ TMCB

Dual-kinase inhibitor; inhibits CK2 and ERK8

Manufacturer: Tocris™ 3675/10

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Catalog No. 36-751-0R

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Disclaimers:

For Research Use Only


    Specifications

    Product Type TMCB
    Inhibitors TMCB
    Purity >98
    Molecular Weight 534.82
    Quantity 10mg

    Dual-kinase inhibitor; inhibits both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50µM for both CK2 and ERK8). Displays selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki values are 0.25, 8.65, 11.90 and 15.25µM for CK2, PIM1, DYRK1a and HIPK2 respectively).

    • Chemical Name: 2-(4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)acetic acid
    • Formula: C11H9Br4N3O2
    • CAS Number: 905105-89-7
    • Solubility: Soluble to 25mM in DMSO
    • Purity: >98

  • Description & Specifications

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