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TMEM59 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 241341AP

Catalog No. 50-173-4244


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Description

Description

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
Specifications

Specifications

TMEM59
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9BXS4
C1orf8, HSPC001, Liver membrane bound protein, TMEM59, transmembrane protein 59, UNQ169/PRO195
Rabbit
IgG
150 μL
-20°C
Primary
9528
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
TMEM59
Liquid
TMEM59
TMEM59 Fusion Protein Ag21150
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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