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TMPRSS11F Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550846

Catalog No. PA550846


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Description

Description

The antibody detects endogenous levels of total TMPRSS11F protein.

TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
Specifications

Specifications

TMPRSS11F
Polyclonal
Unconjugated
TMPRSS11F
Liquid
TMPRSS11F
Synthetic peptide corresponding to residues near the C terminal of human transmembrane protease, serine 11F
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
2 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q6ZWK6, Q8BHM9
HATL4
Rabbit
IgG
100 μL
-20°C
Primary
243083, 389208
Documents
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