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CD263 (TRAIL-R3) Mouse anti-Human, FITC, Clone: TRAIL-R3-02, Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen A15751

Catalog No. 50-113-7749


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Description

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Specifications

Specifications

CD263 (TRAIL-R3)
Monoclonal
0.1 mg/mL
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
O14798
CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID
Mouse
IgG1
100 μg
4° C
Primary
8794
Flow Cytometry
TRAIL-R3-02
FITC
TNFRSF10C
Liquid
TNFRSF10C
Human CD263
Purified
RUO
Antibody
Monoclonal
Human
Documents
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