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TNFRSF13B Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 215201AP

Catalog No. 50-173-3461


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Description

Description

Simultaneously four different laboratories identified a a new member of the tumor necrosis factor (TNF) family. This has been named as TALL-1 (1), THANK (TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase (2), BAFF (for B cell activating factor belonging to the TNF family) (3) and BlyS (B lymphocyte stimulator). Membrane-bound BAFF is processed and secreted through the action of a protease whose specificity matches that of the furin family of proprotein convertases. The receptor for BlyS/BAFF appears to be expressed predomitly on B cells and activated T cells. Recently two orphan receptors TACI (6) and BCMA (,8) have been shown to be receptors for BlyS/BAFF (6-9). TACI is expressed on B cells and signals through CAML, activating the transcription factors NF-AT, NF-kB, and AP-1. TACI is a type III transmembrane protein, as defined by the lack of a cleaved signal sequence and its N-terminal extracellular exposure. The cDNA codes for 293 amino acids with predicted molecular weight of approximately 32 kDa.
Specifications

Specifications

TNFRSF13B
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O14836
CD267, CVID, TACI, TNFRSF13B, TNFRSF14B
Rabbit
IgG
150 μL
-20°C
Primary
23495
Western Blot
Unconjugated
TNFRSF13B
Liquid
TNFRSF13B
TNFRSF13B Fusion Protein Ag16097
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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