TNFRSF13C Mouse anti-Human, Clone: 11C1, Abnova™
Mouse monoclonal antibody raised against human TNFRSF13C.
Manufacturer: Abnova Corporation MAB12949
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq]
|Mouse monoclonal antibody raised against human TNFRSF13C.|
|In PBS, pH 7.2 (0.09% sodium azide).|
|Store at 4°C. Do not freeze.|
|Flow Cytometry, Immunohistochemistry (PFA fixed)|
|Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user.|
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