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TNFSF8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 178521AP

Catalog No. 50-173-1833


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Description

Description

The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin ft.s disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin ft.s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin ft.s lymphomas (including Burkitt ft.s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
Specifications

Specifications

TNFSF8
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P32971, P32972
CD153, CD30 L, CD30 ligand, CD30L, CD30LG, TNFSF8
Rabbit
IgG
150 μL
-20°C
Primary
21949, 683163, 944
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
TNFSF8
Liquid
TNFSF8
TNFSF8 Fusion Protein Ag12303
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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