TNNC1 Monoclonal Antibody (OTI8F8), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804501

Catalog No. 50-168-0276

Description

Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.

Specifications

• Antigen: TNNC1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P63316
• Gene Symbols: TNNC1
• Immunogen: Full length human recombit protein of human TNNC1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI8F8
• Conjugate: Unconjugated
• Gene: TNNC1
• Gene Alias: CMD1Z, CMH13, TN-C, TNC, TNNC
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7134
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid