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TNNI2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 221301AP

Catalog No. 50-173-3735


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Description

Description

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.
Specifications

Specifications

TNNI2
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P13412, P27768, P48788
AMCD2B, DA2B, FSSV, fsTnI, TNNI2, Troponin I fast skeletal muscle, Troponin I, fast-twitch isoform
Rabbit
IgG
150 μL
-20°C
Primary
21953, 29389, 7136
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
TNNI2
Liquid
TNNI2
TNNI2 Fusion Protein Ag17750
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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