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Tocris Bioscience™ Catestatin

Non-competitive nicotinic cholinergic antagonist

Supplier:  Tocris Bioscience™ 2722/1

Catalog No. 27-221


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Description

Description

Non-competitive nAChR antagonist

Catestatin is a non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ∽ 200 nM). Blocks nicotinic-induced cationic signaling (IC50 ∽ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release. Also stimulates mast cell release of histamine via a separate mechanism.
Specifications

Specifications

1 mg
SDS
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