Invitrogen™ TOM70 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA146188

Catalog No. PA146188

Description

Suggested positive control: purified mitochondrial extracts and HeLa whole cell extract.

Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators (import components). Proteins to be imported are chaperoned to the mitochondria by the cytosolic heat shock protein (cHSP70) and are immediately pursued by Translocators of the Outer Membrane (TOMs), followed by transient interactions of the unfolded proteins with Translocators of the Inner Membrane (TIMs). TOMM70A is ubiquitously expressed in human tissues and localizes in the mitochondria. TOMM70A could play a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and the uncoupling proteins.

Specifications

• Antigen: TOM70
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TOMM70
• Gene Alias: 2610044B22Rik; D16Ium22; D16Ium22e; D16Wsu109e; FLJ90470; KIAA0719; Mitochondrial import receptor subunit TOM70; mitochondrial precursor proteins import receptor; mKIAA0719; Tom70; Tomm70; Tomm70a; Translocase of outer membrane 70 kDa subunit; translocase of outer mitochondrial membrane 70; translocase of outer mitochondrial membrane 70 homolog A; translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae); translocase of outer mitochondrial membrane 70 homolog A (yeast); translocase of outer mitochondrial membrane protein 70
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100352274, 28185, 304017, 9868
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O94826, Q75Q39, Q9CZW5
• Gene Symbols: TOMM70, Tomm70a
• Immunogen: A synthetic peptide made to a region within residues 1-100 of the human TOM70 protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov