Invitrogen™ TOP1MT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104428

Catalog No. PIPA5104428

Description

Antibody detects endogenous levels of total TOP1MT.

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: TOP1MT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TOP1MT
• Gene Alias: 2900052H09Rik; DNA topoisomerase 1, mitochondrial; DNA topoisomerase I; DNA topoisomerase I, mitochondrial; mitochondrial topoisomerase I; mitochondrial topoisomerase IB; TOP1M; TOP1MT; topoisomerase (DNA) I, mitochondrial; Topoisomerase I mitochondrial; Type IB Topoisomerase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116447, 300029, 72960
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6IM78, Q8R4U6, Q969P6
• Gene Symbols: TOP1MT
• Immunogen: A synthesized peptide derived from human TOP1MT(Accession Q969P6), corresponding to amino acid residues H203-T253.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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