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Thermo Scientific™ Lab Vision™ Topoisomerase II α Ab-1, Rabbit Polyclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Topoisomerase II α Ab-1, Rabbit Polyclonal Antibody.

Specifications

Antigen Topoisomerase II alpha Ab-1
Concentration 1mg/mL
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
RB117P0
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Thermo Scientific™
RB117P0
Purified Ab with BSA and Azide 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ Topoisomerase II α Ab-1, Rabbit Polyclonal Antibody.

Topo IIα plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Note that Ki67/M1B1 is also present in G1-phase. Topo IIα is also implicated in drug resistance of tumor cells.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not known.

Epitope: aa 1513-1530

Immunogen: A synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIα

Molecular Weight: 170kDa

Positive Control: Raji cells or any exponentially growing cultured human cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Topoisomerase II alpha Ab-1
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
Rabbit
DNA Repair
A synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIalpha
1mg/mL
Polyclonal
Concentrated
RUO
Primary
IgG
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