UHRF1 Mouse anti-Human, Mouse, Clone: 2A11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524865
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
|Synthetic peptide corresponding to the N-terminus of Human UHRF1|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.4|
|Np95; hNP95; ICBP90; RNF106; FLJ21925; MGC138707; E3 ubiquitin-protein ligase UHRF1; Nuclear protein 95; HuNp95; hNp95; RING finger protein 106;|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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