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  8. TP 003, Tocris Bioscience™

TP 003, Tocris Bioscience™

Catalog No. p-4816989
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

GABAA partial agonist; acts at benzodiazepine site

GABAA receptor partial agonist that demonstrates affinity for the benzodiazepine site. Potentiates GABAA α3 response with high efficacy. Produces anxiolytic-like effects in rodent elevated plus maze via action at GABAA α2 subtype receptors. Also evokes GABAA α1 mediated sedation and GABAA α3 mediated muscle relaxation in mice.

Chemical Identifiers

CAS 628690-75-5
Molecular Formula C23H16F3N3O
Molecular Weight (g/mol) 407.396
InChI Key SJMMDWXJSSJHOQ-UHFFFAOYSA-N
Synonym d0q1zt, 2',4-difluoro-5'-8-fluoro-7-1-hydroxy-1-methylethyl imidazo 1,2-a-pyridin-3-yl-1,1'-biphenyl-2-carbonitrile, 5-fluoro-2-2-fluoro-5-8-fluoro-7-2-hydroxypropan-2-yl imidazo 1,2-a pyridin-3-yl phenyl benzonitrile
PubChem CID 10001434
IUPAC Name 5-fluoro-2-[2-fluoro-5-[8-fluoro-7-(2-hydroxypropan-2-yl)imidazo[1,2-a]pyridin-3-yl]phenyl]benzonitrile
SMILES CC(C)(C1=C(C2=NC=C(N2C=C1)C3=CC(=C(C=C3)F)C4=C(C=C(C=C4)F)C#N)F)O

Specifications

Quantity 10 mg
Formula Weight 407.39
Percent Purity >98%
Chemical Name or Material TP 003

Safety and Handling

Recommended Storage Store at +4°C
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