TPM4 Monoclonal Antibody (TM228), Invitrogen™

Catalog No.	Quantity
PIMA532983	100 μg

Catalog No. PIMA532983

Supplier: Thermo Scientific MA532983

Description

Mouse Monoclonal Antibody

Reconstitution information: Add 1 mL of PBS buffer will yield a concentration of 100 μg/mL.

TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: TPM4
• Applications: Immunohistochemistry (Frozen), Western Blot
• Classification: Monoclonal
• Clone: TM228
• Conjugate: Unconjugated
• Formulation: Ascites diluted in 1.2% sodium acetate with 2MG BSA, 2MG BSA and 0.01MG sodium azide, 0.01MG sodium azide
• Gene: TPM4
• Gene Accession No.: P67936
• Gene Alias: Tropomyosin alpha-4 chain; Tropomyosin-4; TM-4; Tpm4
• Gene Symbols: TPM4
• Host Species: Mouse
• Immunogen: Chicken gizzard tropomyosin.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100343175, 107055375, 7171
• Target Species: Chicken, Human, Rabbit
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a