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TPMT Mouse anti-Human, Clone: OTI5B4, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA500965

Catalog No. 50-167-2106


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Description

Description

Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine. Defects in TPMT are the cause of thiopurine S-methyltransferase deficiency (TPMT deficiency).TPMT is an enzyme involved in the normal metabolic inactivation of thiopurine drugs. These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation. Patients with intermediate or no TPMT activity are at risk of toxicity after receiving standard doses of thiopurine drugs and it is shown that inter-individual differences in response to these drugs are largely determined by genetic variation at the TPMT locus.
Specifications

Specifications

TPMT
Monoclonal
0.6 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P51580
TPMTD
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7172
Immunohistochemistry (Paraffin), Western Blot
OTI5B4
Unconjugated
TPMT
Liquid
TPMT
Full length human recombit protein of human TPMT produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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