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TRAM 39, Tocris Bioscience™

Potent KCa3.1 blocker

Manufacturer:  Tocris Bioscience 4952/5

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Catalog No. 49-525


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Description

Description

Potent intermediate conductance Ca2+-activated K+ channel (KCa3.1) blocker (Kd = 60 nM). Has no effect on cytochrome p450 activity. Inhibits I-EBIO -stimulated increases in rat artery membrane potential ex vivo. Also diminishes LPS-induced cryptidin (mammalian α-defensin) release from paneth cells in vitro.
Specifications

Specifications

2-Chloro-α,α-diphenylbenzeneacetonitrile
>99%
Observed MW: 303.78
197525-99-8
C20H14ClN
5mg
Safety and Handling

Safety and Handling

Recommended Storage : Store at Room Temperature

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