TRIB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 153591AP
DescriptionThis gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|C5FW, GS3955, TRB 2, TRB2, TRIB2, Tribbles homolog 2|
|217410, 28951, 313974|
|Immunohistochemistry (Paraffin), Western Blot|
|TRIB2 Fusion Protein Ag7605|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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