Trichloromethyl chloroformate, 98%, Thermo Scientific Chemicals

Description

Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.

Solubility
Miscible with ethanol, ether and benzene. Immiscible with water.

Notes
Special handling precautions required. View MSDS prior to purchase. MSDS are available online at www.alfa.comStore in a cool place. Light and heat sensitive. Incompatible with strong oxidizing agents and bases.

Specifications

• Melting Point: °C to 57°C
• Density: 1.640 g/mL
• Boiling Point: 128°C
• Flash Point: >110°C (230°F)
• Assay Percent Range: 98%
• Refractive Index: 1.457
• Linear Formula: CO₂CCl₃
• Quantity: 10 g
• UN Number: UN3390
• Beilstein: 970225
• Sensitivity: Moisture sensitive
• Merck Index: 14,3334
• Solubility Information: Miscible with ethanol,ether and benzene. Immiscible with water.
• Formula Weight: 197.83
• Percent Purity: 98%
• Chemical Name or Material: Trichloromethyl chloroformate

Safety and Handling

Hazard Category	H300+H330-H314
Hazard Statement	GHS H Statement H330-H314-H318
Precautionary Statement	P260-P262-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC BY INHALATION LIQUID, CORROSIVE, N.O.S.
EINECSNumber	207-965-9
RTECSNumber	LQ7350000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only