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TRIM27 Mouse anti-Human, Clone: OTI3B12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526641

Catalog No. PIMA526641


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Description

Description

TRIM27, also designated Ret finger protein (RFP), is a member of the tripartite motif family, which is characterized by a conserved RING finger, a B-box and a coiled-coil domain (together designated RBCC). TRIM27 becomes oncogenic when its RBCC is fused with the tyrosine kinase domain of the RET protein.Normally, TRIM27 functions as a transcriptional repressor and associates with enhancer of polycomb (EPC1) and Mi-2beta, a main component of the nucleosome remodeling and deacetylase (NuRD) complex. TRIM27 is expressedat specific stages of spermatogenesis and in various tissues and can be localized to either the cytoplasm or nucleus depending on the cell type.
Specifications

Specifications

TRIM27
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P14373
RFP, RNF76, RFP transforming protein, RING finger protein 76, ret finger protein, tripartite motif protein TRIM27, tripartite motif-containing 27, tripartite motif-containing protein 27, zinc finger protein RFP
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5987
Immunohistochemistry (Paraffin), Western Blot
OTI3B12
Unconjugated
TRIM27
Liquid
TRIM27
Full length human recombit protein of TRIM27 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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