TRIM27 Mouse anti-Human, Clone: OTI4D4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526635
DescriptionTRIM27, also designated Ret finger protein (RFP), is a member of the tripartite motif family, which is characterized by a conserved RING finger, a B-box and a coiled-coil domain (together designated RBCC). TRIM27 becomes oncogenic when its RBCC is fused with the tyrosine kinase domain of the RET protein.Normally, TRIM27 functions as a transcriptional repressor and associates with enhancer of polycomb (EPC1) and Mi-2beta, a main component of the nucleosome remodeling and deacetylase (NuRD) complex. TRIM27 is expressedat specific stages of spermatogenesis and in various tissues and can be localized to either the cytoplasm or nucleus depending on the cell type.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|RFP, RNF76, RFP transforming protein, RING finger protein 76, ret finger protein, tripartite motif protein TRIM27, tripartite motif-containing 27, tripartite motif-containing protein 27, zinc finger protein RFP|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of TRIM27 produced in E.coli|
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